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Autophagy is a novel pathway for neurofilament protein degradation in vivo
How macroautophagy/autophagy influences neurofilament (NF) proteins in neurons, a frequent target in neurodegenerative diseases and injury, is not known. NFs in axons have exceptionally long half-lives in vivo enabling formation of large stable supporting networks, but they can be rapidly degraded d...
Autores principales: | Rao, Mala V., Darji, Sandipkumar, Stavrides, Philip H., Goulbourne, Chris N., Kumar, Asok, Yang, Dun-Sheng, Yoo, Lang, Peddy, James, Lee, Ju-Hyun, Yuan, Aidong, Nixon, Ralph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012948/ https://www.ncbi.nlm.nih.gov/pubmed/36131358 http://dx.doi.org/10.1080/15548627.2022.2124500 |
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