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Sensitization of supra-threshold pain responses—Translational aspects and mechanisms

A substantial translational gap in pain research has been reflected by a mismatch of relevant primary pain assessment endpoints in preclinical vs. clinical trials. Since activity-dependent mechanisms may be neglected during reflexive tests, this may add as a confounding factor during preclinical pai...

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Detalles Bibliográficos
Autores principales: Jonas, Robin, Schmelz, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013001/
https://www.ncbi.nlm.nih.gov/pubmed/36926107
http://dx.doi.org/10.3389/fnetp.2022.1078890