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Sensitization of supra-threshold pain responses—Translational aspects and mechanisms
A substantial translational gap in pain research has been reflected by a mismatch of relevant primary pain assessment endpoints in preclinical vs. clinical trials. Since activity-dependent mechanisms may be neglected during reflexive tests, this may add as a confounding factor during preclinical pai...
Autores principales: | Jonas, Robin, Schmelz, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013001/ https://www.ncbi.nlm.nih.gov/pubmed/36926107 http://dx.doi.org/10.3389/fnetp.2022.1078890 |
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