Cargando…

Increased RTN3 phenocopies nonalcoholic fatty liver disease by inhibiting the AMPK–IDH2 pathway

Reticulon 3 (RTN3), an endoplasmic reticulum protein, is crucial in neurodegenerative and kidney diseases. However, the role of RTN3 in liver tissues has not been described. Here, we employed public datasets, patients, and several animal models to explore the role of RTN3 in nonalcoholic fatty liver...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Hao, Guo, Shuai, Chen, Ya‐Qin, Liu, Yu‐Xing, Jin, Jie‐Yuan, Liang, Yun, Fan, Liang‐Liang, Xiang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013133/
https://www.ncbi.nlm.nih.gov/pubmed/36925557
http://dx.doi.org/10.1002/mco2.226