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Design, biological evaluation, and molecular modelling insights of cupressic acid derivatives as promising anti-inflammatory agents

The major labdanes in the oleogum resin of Araucaria heterophylla (Salisb.) Franco, 13-epi-cupressic acid (1) and acetyl-13-epi-cupressic acid (2) were used to prepare seven new (3–9), along with one known (10) derivatives. RAW264.7 cells were used to evaluate the anti-inflammatory activity of the d...

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Detalles Bibliográficos
Autores principales: Soliman, Amal F., Elimam, Diaaeldin M., El-Senduny, Fardous F., Alossaimi, Manal A., Alamri, Mubarak, Abdel Bar, Fatma M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013213/
https://www.ncbi.nlm.nih.gov/pubmed/36912259
http://dx.doi.org/10.1080/14756366.2023.2187327