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Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein

SARS-CoV-2 spike glycoprotein mediates receptor binding and subsequent membrane fusion. It exists in a range of conformations, including a closed state unable to bind the ACE2 receptor, and an open state that does so but displays more exposed antigenic surface. Spikes of variants of concern (VOCs) a...

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Detalles Bibliográficos
Autores principales: Calvaresi, Valeria, Wrobel, Antoni G., Toporowska, Joanna, Hammerschmid, Dietmar, Doores, Katie J., Bradshaw, Richard T., Parsons, Ricardo B., Benton, Donald J., Roustan, Chloë, Reading, Eamonn, Malim, Michael H., Gamblin, Steve J., Politis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013288/
https://www.ncbi.nlm.nih.gov/pubmed/36918534
http://dx.doi.org/10.1038/s41467-023-36745-0