Colchicine reduces the activation of NLRP3 inflammasome in COVID-19 patients

OBJECTIVE: To evaluate whether colchicine treatment was associated with the inhibition of NLRP3 inflammasome activation in patients with COVID-19. METHODS: We present a post hoc analysis from a double-blinded placebo-controlled randomized clinical trial (RCT) on the effect of colchicine for the trea...

Descripción completa

Detalles Bibliográficos
Autores principales: Amaral, N. B., Rodrigues, T. S., Giannini, M. C., Lopes, M. I., Bonjorno, L. P., Menezes, P. I. S. O., Dib, S. M., Gigante, S. L. G., Benatti, M. N., Rezek, U. C., Emrich-Filho, L. L., Sousa, B. A., Almeida, S. C. L., Luppino-Assad, R., Veras, F. P., Schneider, A. H., Leiria, L. O. S., Cunha, L. D., Alves-Filho, J. C., Cunha, T. M., Arruda, E., Miranda, C. H., Pazin-Filho, A., Auxiliadora-Martins, M., Borges, M. C., Fonseca, B. A. L., Bollela, V. R., Del-Ben, C. M., Cunha, F. Q., Santana, R. C., Vilar, F. C., Zamboni, D. S., Louzada-Junior, P., Oliveira, R. D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013297/
https://www.ncbi.nlm.nih.gov/pubmed/36917217
http://dx.doi.org/10.1007/s00011-023-01718-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013297/
https://www.ncbi.nlm.nih.gov/pubmed/36917217
http://dx.doi.org/10.1007/s00011-023-01718-y

Ejemplares similares