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Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII

Carbonic anhydrases (CAs) are important regulators of pH homeostasis and participate in many physiological and pathological processes. CA activators (CAAs) are becoming increasingly important in the biomedical field since enhancing CA activity may have beneficial effects at neurological level. Here,...

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Detalles Bibliográficos
Autores principales: Fiorentino, Francesco, Nocentini, Alessio, Rotili, Dante, Supuran, Claudiu T., Mai, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013323/
https://www.ncbi.nlm.nih.gov/pubmed/36912265
http://dx.doi.org/10.1080/14756366.2023.2188147