Knocking down GALNT6 promotes pyroptosis of pancreatic ductal adenocarcinoma cells through NF-κB/NLRP3/GSDMD and GSDME signaling pathway

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC), the most prevalent type of pancreatic cancer, is a highly lethal malignancy with poor prognosis. Polypeptide N-acetylgalactosaminyltransferase-6 (GALNT6) is frequently overexpressed in PDAC. However, the role of GALNT6 in the PDAC remains unclear....

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Detalles Bibliográficos
Autores principales: Ding, Mengyang, Liu, Jingyu, Lv, Honghui, Zhu, Yanlin, Chen, Yumiao, Peng, Hui, Fan, Sairong, Chen, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013470/
https://www.ncbi.nlm.nih.gov/pubmed/36925932
http://dx.doi.org/10.3389/fonc.2023.1097772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013470/
https://www.ncbi.nlm.nih.gov/pubmed/36925932
http://dx.doi.org/10.3389/fonc.2023.1097772

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