Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII

The Carbonic anhydrase isoforms IX and XII play a significant role in regulating the intracellular and extracellular pH in hypoxic tumours abetting the metastasis of solid tumours. Selective and potent inhibitors targeting carbonic anhydrase IX and XII reduce the activity of these isoforms in hypoxi...

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Detalles Bibliográficos
Autores principales: Mahammad Ghouse, Shaik, Bahatam, Kavyaraj, Angeli, Andrea, Pawar, Gaurav, Chinchilli, Krishna Kartheek, Yaddanapudi, Venkata Madhavi, Mohammed, Arifuddin, Supuran, Claudiu T., Nanduri, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013565/
https://www.ncbi.nlm.nih.gov/pubmed/36876597
http://dx.doi.org/10.1080/14756366.2023.2185760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013565/
https://www.ncbi.nlm.nih.gov/pubmed/36876597
http://dx.doi.org/10.1080/14756366.2023.2185760

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