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Effect of Food on the Pharmacokinetics and Safety of a Novel c-Met Inhibitor SCC244: A Randomized Phase I Study in Healthy Subjects

OBJECTIVE: This study aimed to investigate the effect of food on the pharmacokinetics and safety profiles of SCC244, a novel oral c-Met inhibitor in healthy Chinese male subjects. METHODS: It was a randomized, open-label, and 3-period crossover design, single-dose phase I clinical trial. A total of...

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Detalles Bibliográficos
Autores principales: Wu, Juan, Xu, Hongrong, Li, Hui, Ma, Lei, Chen, Juan, Yuan, Fei, Sheng, Lei, Liu, Chao, Chen, Weili, Li, Xuening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013581/
https://www.ncbi.nlm.nih.gov/pubmed/36925997
http://dx.doi.org/10.2147/DDDT.S388846