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Effect of Food on the Pharmacokinetics and Safety of a Novel c-Met Inhibitor SCC244: A Randomized Phase I Study in Healthy Subjects
OBJECTIVE: This study aimed to investigate the effect of food on the pharmacokinetics and safety profiles of SCC244, a novel oral c-Met inhibitor in healthy Chinese male subjects. METHODS: It was a randomized, open-label, and 3-period crossover design, single-dose phase I clinical trial. A total of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013581/ https://www.ncbi.nlm.nih.gov/pubmed/36925997 http://dx.doi.org/10.2147/DDDT.S388846 |