State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells

SMAD-mediated signaling regulates apoptosis, cell cycle arrest, and epithelial-to-mesenchymal transition to safeguard tissue homeostasis. However, it remains elusive how the relatively simple pathway can determine such a broad range of cell fate decisions and how it differentiates between varying li...

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Detalles Bibliográficos
Autores principales: Bohn, Stefan, Hexemer, Lorenz, Huang, Zixin, Strohmaier, Laura, Lenhardt, Sonja, Legewie, Stefan, Loewer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013741/
https://www.ncbi.nlm.nih.gov/pubmed/36857347
http://dx.doi.org/10.1073/pnas.2210891120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013741/
https://www.ncbi.nlm.nih.gov/pubmed/36857347
http://dx.doi.org/10.1073/pnas.2210891120

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