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State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells
SMAD-mediated signaling regulates apoptosis, cell cycle arrest, and epithelial-to-mesenchymal transition to safeguard tissue homeostasis. However, it remains elusive how the relatively simple pathway can determine such a broad range of cell fate decisions and how it differentiates between varying li...
Autores principales: | Bohn, Stefan, Hexemer, Lorenz, Huang, Zixin, Strohmaier, Laura, Lenhardt, Sonja, Legewie, Stefan, Loewer, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013741/ https://www.ncbi.nlm.nih.gov/pubmed/36857347 http://dx.doi.org/10.1073/pnas.2210891120 |
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