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Current progress of cerebral organoids for modeling Alzheimer's disease origins and mechanisms

Alzheimer's disease (AD) is a progressive, neurodegenerative disease that has emerged as a leading risk factor for dementia associated with increasing age. Two‐dimensional (2D) cell culture and animal models, which have been used to analyze AD pathology and search for effective treatments for d...

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Detalles Bibliográficos
Autores principales: Sreenivasamurthy, Sai, Laul, Mahek, Zhao, Nan, Kim, Tiffany, Zhu, Donghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013781/
https://www.ncbi.nlm.nih.gov/pubmed/36925717
http://dx.doi.org/10.1002/btm2.10378