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Metal–Phenolic Network-Facilitated “Foe-to-Friend” Conversion of Melittin for Cancer Immunotherapy with Boosted Abscopal Effect

As a naturally occurring cytolytic peptide, melittin (Mel) has strong cytolytic activity and is a potent therapeutic peptide for cancer therapy. However, the serious hemolytic activity of Mel largely impedes its clinical applications. In this work, based on the strong interactions between proteins/p...

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Detalles Bibliográficos
Autores principales: Guo, Yuxin, Zhang, Xinping, Wang, Shao-Zhe, Feng, Hui-Heng, Wu, Shun-Yu, Wu, Fu-Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013787/
https://www.ncbi.nlm.nih.gov/pubmed/36930774
http://dx.doi.org/10.34133/research.0052