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Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive stranded RNA virus which has caused the recent deadly pandemic called COVID-19. The SARS-CoV-2 virion is coated with a heavily glycosylated Spike glycoprotein which is responsible for attachment and entry into targ...

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Detalles Bibliográficos
Autores principales: Muñoz-Basagoiti, Jordana, Monteiro, Fábio Luís Lima, Krumpe, Lauren R. H., Armario-Najera, Victoria, Shenoy, Shilpa R., Perez-Zsolt, Daniel, Westgarth, Harrison James, Villorbina, Gemma, Bomfim, Larissa Maciel, Raïch-Regué, Dàlia, Nogueras, Lara, Henrich, Curtis J., Gallemí, Marçal, Moreira, Filipe Romero Rebello, Torres, Pascual, Wilson, Jennifer, D’arc, Mirela, Marfil, Silvia, Herlinger, Alice Laschuk, Pradenas, Edwards, Higa, Luiza Mendonça, Portero-Otin, Manuel, Trinité, Benjamin, Twyman, Richard M., Capell, Teresa, Tanuri, Amilcar, Blanco, Julià, Izquierdo-Useros, Nuria, Rech, Elibio L., Christou, Paul, O’Keefe, Barry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013841/
https://www.ncbi.nlm.nih.gov/pubmed/36853940
http://dx.doi.org/10.1073/pnas.2214561120