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Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport

Major Facilitator Superfamily Domain containing 2a (Mfsd2a) is a sodium-dependent lysophosphatidylcholine (LPC) transporter expressed at the blood–brain barrier that constitutes the main pathway by which the brain obtains omega-3 fatty acids, such as docosahexanoic acid. Mfsd2a deficiency in humans...

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Detalles Bibliográficos
Autores principales: Chua, Geok-Lin, Tan, Bryan C., Loke, Randy Y. J., He, Menglan, Chin, Cheen-Fei, Wong, Bernice H., Kuk, Alvin C. Y., Ding, Mei, Wenk, Markus R., Guan, Lan, Torta, Federico, Silver, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013850/
https://www.ncbi.nlm.nih.gov/pubmed/36848557
http://dx.doi.org/10.1073/pnas.2215290120