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Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport
Major Facilitator Superfamily Domain containing 2a (Mfsd2a) is a sodium-dependent lysophosphatidylcholine (LPC) transporter expressed at the blood–brain barrier that constitutes the main pathway by which the brain obtains omega-3 fatty acids, such as docosahexanoic acid. Mfsd2a deficiency in humans...
Autores principales: | Chua, Geok-Lin, Tan, Bryan C., Loke, Randy Y. J., He, Menglan, Chin, Cheen-Fei, Wong, Bernice H., Kuk, Alvin C. Y., Ding, Mei, Wenk, Markus R., Guan, Lan, Torta, Federico, Silver, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013850/ https://www.ncbi.nlm.nih.gov/pubmed/36848557 http://dx.doi.org/10.1073/pnas.2215290120 |
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