Genome-wide maps of rare and atypical UV photoproducts reveal distinct patterns of damage formation and mutagenesis in yeast chromatin

Ultraviolet (UV) light induces different classes of mutagenic photoproducts in DNA, namely cyclobutane pyrimidine dimers (CPDs), 6-4 photoproducts (6-4PPs), and atypical thymine–adenine photoproducts (TA-PPs). CPD formation is modulated by nucleosomes and transcription factors (TFs), which has impor...

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Detalles Bibliográficos
Autores principales: Bohm, Kaitlynne A., Morledge-Hampton, Benjamin, Stevison, Scott, Mao, Peng, Roberts, Steven A., Wyrick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013872/
https://www.ncbi.nlm.nih.gov/pubmed/36853943
http://dx.doi.org/10.1073/pnas.2216907120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013872/
https://www.ncbi.nlm.nih.gov/pubmed/36853943
http://dx.doi.org/10.1073/pnas.2216907120

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