Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex

Autism spectrum disorder (ASD) is a highly heterogeneous disorder, yet transcriptomic profiling of bulk brain tissue has identified substantial convergence among dysregulated genes and pathways in ASD. However, this approach lacks cell-specific resolution. We performed comprehensive transcriptomic a...

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Detalles Bibliográficos
Autores principales: Zhang, Pan, Omanska, Alicja, Ander, Bradley P., Gandal, Michael J., Stamova, Boryana, Schumann, Cynthia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013873/
https://www.ncbi.nlm.nih.gov/pubmed/36862688
http://dx.doi.org/10.1073/pnas.2206758120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013873/
https://www.ncbi.nlm.nih.gov/pubmed/36862688
http://dx.doi.org/10.1073/pnas.2206758120

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