Clonal isolates of Treponema pallidum subsp. pallidum Nichols provide evidence for the occurrence of microevolution during experimental rabbit infection and in vitro culture

The recent development of a system for long-term in vitro culture of the syphilis spirochete, Treponema pallidum subsp. pallidum, has introduced the possibility of detailed genetic analysis of this bacterium. In this study, the in vitro culture system was used to isolate and characterize clonal popu...

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Detalles Bibliográficos
Autores principales: Edmondson, Diane G., De Lay, Bridget D., Hanson, Blake M., Kowis, Lindsay E., Norris, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013896/
https://www.ncbi.nlm.nih.gov/pubmed/36917571
http://dx.doi.org/10.1371/journal.pone.0281187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013896/
https://www.ncbi.nlm.nih.gov/pubmed/36917571
http://dx.doi.org/10.1371/journal.pone.0281187

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