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Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils

Neisseria gonorrhoeae (Gc) is a human-specific pathogen that causes the sexually transmitted infection gonorrhea. Gc survives in neutrophil-rich gonorrheal secretions, and recovered bacteria predominantly express phase-variable, surface-expressed opacity-associated (Opa) proteins (Opa+). However, ex...

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Detalles Bibliográficos
Autores principales: Werner, Lacie M., Alcott, Allison, Mohlin, Frida, Ray, Jocelyn C., Belcher Dufrisne, Meagan, Smirnov, Asya, Columbus, Linda, Blom, Anna M., Criss, Alison K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013916/
https://www.ncbi.nlm.nih.gov/pubmed/36862761
http://dx.doi.org/10.1371/journal.ppat.1011055