Rigidified Bis(sulfonyl)ethylenes as Effective Michael Acceptors for Asymmetric Catalysis: Application to the Enantioselective Synthesis of Quaternary Hydantoins

[Image: see text] The catalytic, enantio- and diastereoselective addition of hydantoin surrogates II to “rigidified” vinylidene bis(sulfone) reagents is developed, thus overcoming the inability of commonly employed β-substituted vinylic sulfones to react. Adducts are transformed in enantioenriched 5...

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Detalles Bibliográficos
Autores principales: Villaescusa, Leire, Hernández, Iker, Azcune, Laura, Rudi, Ainhoa, Mercero, José M., Landa, Aitor, Oiarbide, Mikel, Palomo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013931/
https://www.ncbi.nlm.nih.gov/pubmed/36630318
http://dx.doi.org/10.1021/acs.joc.2c02403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013931/
https://www.ncbi.nlm.nih.gov/pubmed/36630318
http://dx.doi.org/10.1021/acs.joc.2c02403

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