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Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer

Platinum-based chemotherapy remains the main systemic treatment of ovarian cancer (OC). However, the inevitable development of platinum and poly (adenosine diphosphate-ribose) polymerase inhibitor (PARPi) resistance is associated with poor outcomes, which becomes a major obstacle in the management o...

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Detalles Bibliográficos
Autores principales: Li, Yangyang, Cen, Yixuan, Tu, Mengyan, Xiang, Zhenzhen, Tang, Sangsang, Lu, Weiguo, Zhang, Hongbo, Xu, Junfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013963/
https://www.ncbi.nlm.nih.gov/pubmed/36930754
http://dx.doi.org/10.34133/research.0070