FOXO3A‐short is a novel regulator of non‐oxidative glucose metabolism associated with human longevity

Intronic single‐nucleotide polymorphisms (SNPs) in FOXO3A are associated with human longevity. Currently, it is unclear how these SNPs alter FOXO3A functionality and human physiology, thereby influencing lifespan. Here, we identify a primate‐specific FOXO3A transcriptional isoform, FOXO3A‐Short (FOX...

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Detalles Bibliográficos
Autores principales: Santo, Evan E., Ribel‐Madsen, Rasmus, Stroeken, Peter J., de Boer, Vincent C. J., Hansen, Ninna S., Commandeur, Maaike, Vaag, Allan A., Versteeg, Rogier, Paik, Jihye, Westerhout, Ellen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014046/
https://www.ncbi.nlm.nih.gov/pubmed/36617632
http://dx.doi.org/10.1111/acel.13763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014046/
https://www.ncbi.nlm.nih.gov/pubmed/36617632
http://dx.doi.org/10.1111/acel.13763

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