Quantitative systems pharmacology model of GITR‐mediated T cell dynamics in tumor microenvironment

T cell interaction in the tumor microenvironment is a key component of immuno‐oncology therapy. Glucocorticoid‐induced tumor necrosis factor receptor (TNFR)‐related protein (GITR) is expressed on immune cells including regulatory T cells (Tregs) and effector T cells (Teffs). Preclinical data suggest...

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Detalles Bibliográficos
Autores principales: Ji, Yan, Madrasi, Kumpal, Knee, Deborah A., Gruenbaum, Lore, Apgar, Joshua F., Burke, John M., Gomes, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014051/
https://www.ncbi.nlm.nih.gov/pubmed/36710369
http://dx.doi.org/10.1002/psp4.12925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014051/
https://www.ncbi.nlm.nih.gov/pubmed/36710369
http://dx.doi.org/10.1002/psp4.12925

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