Cargando…

DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice

Heart failure has reached epidemic proportions in a progressively ageing population. The molecular mechanisms underlying heart failure remain elusive, but evidence indicates that DNA damage is enhanced in failing hearts. Here, we tested the hypothesis that endogenous DNA repair in cardiomyocytes is...

Descripción completa

Detalles Bibliográficos
Autores principales: de Boer, Martine, te Lintel Hekkert, Maaike, Chang, Jiang, van Thiel, Bibi S., Martens, Leonie, Bos, Maxime M., de Kleijnen, Marion G. J., Ridwan, Yanto, Octavia, Yanti, van Deel, Elza D., Blonden, Lau A., Brandt, Renata M. C., Barnhoorn, Sander, Bautista‐Niño, Paula K., Krabbendam‐Peters, Ilona, Wolswinkel, Rianne, Arshi, Banafsheh, Ghanbari, Mohsen, Kupatt, Christian, de Windt, Leon J., Danser, A. H. Jan, van der Pluijm, Ingrid, Remme, Carol Ann, Stoll, Monika, Pothof, Joris, Roks, Anton J. M., Kavousi, Maryam, Essers, Jeroen, van der Velden, Jolanda, Hoeijmakers, Jan H. J., Duncker, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014058/
https://www.ncbi.nlm.nih.gov/pubmed/36756698
http://dx.doi.org/10.1111/acel.13768