The variant senescence‐associated secretory phenotype induced by centrosome amplification constitutes a pathway that activates hypoxia‐inducible factor‐1α

The senescence‐associated secretory phenotype (SASP) can promote paracrine invasion while suppressing tumour growth, thus generating complex phenotypic outcomes. Likewise, centrosome amplification can induce proliferation arrest yet also facilitate tumour invasion. However, the eventual fate of cell...

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Detalles Bibliográficos
Autores principales: Wu, Selwin K., Ariffin, Juliana, Tay, Shu Chian, Picone, Remigio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014068/
https://www.ncbi.nlm.nih.gov/pubmed/36660875
http://dx.doi.org/10.1111/acel.13766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014068/
https://www.ncbi.nlm.nih.gov/pubmed/36660875
http://dx.doi.org/10.1111/acel.13766

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