Cargando…

The variant senescence‐associated secretory phenotype induced by centrosome amplification constitutes a pathway that activates hypoxia‐inducible factor‐1α

The senescence‐associated secretory phenotype (SASP) can promote paracrine invasion while suppressing tumour growth, thus generating complex phenotypic outcomes. Likewise, centrosome amplification can induce proliferation arrest yet also facilitate tumour invasion. However, the eventual fate of cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Selwin K., Ariffin, Juliana, Tay, Shu Chian, Picone, Remigio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014068/ https://www.ncbi.nlm.nih.gov/pubmed/36660875 http://dx.doi.org/10.1111/acel.13766

Ejemplares similares

Erratum to: The variant senescence‐associated secretory phenotype induced by centrosome amplification constitutes a pathway that activates hypoxia‐inducible factor‐1α
Publicado: (2023)

The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation
por: Huna, Anda, et al.
Publicado: (2023)

Impacts of Telomeric Length, Chronic Hypoxia, Senescence, and Senescence-Associated Secretory Phenotype on the Development of Thoracic Aortic Aneurysm
por: Aschacher, Thomas, et al.
Publicado: (2022)

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
por: Ritschka, Birgit, et al.
Publicado: (2017)

Cell senescence, the senescence-associated secretory phenotype, and cancers
por: Langhi Prata, Larissa G. P., et al.
Publicado: (2023)

A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence
por: Meyer, Patrick, et al.
Publicado: (2017)

IFN-γ and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
por: Homann, Lorenzo, et al.
Publicado: (2022)

Colchicine Protects against Ethanol-Induced Senescence and Senescence-Associated Secretory Phenotype in Endothelial Cells
por: Zhou, Huakang, et al.
Publicado: (2023)

Hypoxia-Induced Centrosome Amplification Underlies Aggressive Disease Course in HPV-Negative Oropharyngeal Squamous Cell Carcinomas
por: Mittal, Karuna, et al.
Publicado: (2020)

Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020)

Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease
por: Wang, Wen-Juan, et al.
Publicado: (2017)

Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and death
por: Ogden, A, et al.
Publicado: (2014)

Cortical dynein drives centrosome clustering in cells with centrosome amplification
por: Mercadante, Dayna L., et al.
Publicado: (2023)

BRCA1 transports the DNA damage signal for CDDP‐induced centrosome amplification through the centrosomal Aurora A
por: Qi, Huicheng, et al.
Publicado: (2022)

PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence
por: Singh, Chandra K., et al.
Publicado: (2022)

Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
por: Shumilov, Anatoliy, et al.
Publicado: (2017)

Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4
por: Mittal, Karuna, et al.
Publicado: (2022)

312 Metabolomics Approach to Cellular Senescence: Characterizing the Secretory Phenotype and Metabolism of Irradiation-Induced Senescent Human Pre- Adipocytes
por: Ortiz-Correa, Zinnarky Kiani, et al.
Publicado: (2023)

MLL1 is essential for the senescence-associated secretory phenotype
por: Capell, Brian C., et al.
Publicado: (2016)

The Role of Senescence-Associated Secretory Phenotype in Bone Loss
por: Zhu, Runjiu, et al.
Publicado: (2022)

Antizyme Restrains Centrosome Amplification by Regulating the Accumulation of Mps1 at Centrosomes
por: Kasbek, Christopher, et al.
Publicado: (2010)

Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype
por: Kumari, Ruchi, et al.
Publicado: (2021)

Role of the Beta Catenin Destruction Complex in Mediating Chemotherapy-Induced Senescence-Associated Secretory Phenotype
por: Basu, Dipanjan, et al.
Publicado: (2012)

Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α–Dependent Senescence-Associated Secretory Phenotype
por: Gardner, Sarah E., et al.
Publicado: (2015)

Publisher Correction: Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020)

RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
por: Iovino, Flora, et al.
Publicado: (2006)

Depletion of the oncoprotein Bcl-3 induces centrosome amplification and aneuploidy in cancer cells
por: Zamora, Ruben, et al.
Publicado: (2010)

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
por: Berenjeno, Inma M., et al.
Publicado: (2017)

Clinical implication of centrosome amplification and expression of centrosomal functional genes in multiple myeloma
por: Dementyeva, Elena, et al.
Publicado: (2013)

Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
por: Guan, Yiting, et al.
Publicado: (2020)

Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice
por: Shrestha, Niraj, et al.
Publicado: (2023)

In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
por: Samakkarnthai, Parinya, et al.
Publicado: (2023)

Centrosome Aberrations Associated with Cellular Senescence and p53 Localization at Supernumerary Centrosomes
por: Ohshima, Susumu
Publicado: (2012)

NF90 coordinately represses the senescence-associated secretory phenotype
por: Tominaga-Yamanaka, Kumiko, et al.
Publicado: (2012)

HMGB2 holds the key to the senescence-associated secretory phenotype
por: Guerrero, Ana, et al.
Publicado: (2016)

Suppression of p16 alleviates the senescence-associated secretory phenotype
por: Buj, Raquel, et al.
Publicado: (2021)

IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype
por: Wiggins, Kimberley A., et al.
Publicado: (2019)

Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells
por: Martínez, Jennyfer, et al.
Publicado: (2019)

Zileuton Alleviates Radiation-Induced Cutaneous Ulcers via Inhibition of Senescence-Associated Secretory Phenotype in Rodents
por: Park, Mineon, et al.
Publicado: (2022)

Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype
por: Lentini, Laura, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_uuqo6mjffglmv3m7kmcmjriqej