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Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells

Aggregates of the tau protein are a well-known hallmark of several neurodegenerative diseases, collectively referred to as tauopathies, including frontal temporal dementia and Alzheimer’s disease (AD). Monitoring the transformation process of tau from physiological monomers into pathological oligome...

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Detalles Bibliográficos
Autores principales: Cecon, Erika, Oishi, Atsuro, Luka, Marine, Ndiaye-Lobry, Delphine, François, Arnaud, Lescuyer, Mathias, Panayi, Fany, Dam, Julie, Machado, Patricia, Jockers, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014071/
https://www.ncbi.nlm.nih.gov/pubmed/36917493
http://dx.doi.org/10.7554/eLife.78360