SUMOylation of Na(V)1.2 channels regulates the velocity of backpropagating action potentials in cortical pyramidal neurons

Voltage-gated sodium channels located in axon initial segments (AIS) trigger action potentials (AP) and play pivotal roles in the excitability of cortical pyramidal neurons. The differential electrophysiological properties and distributions of Na(V)1.2 and Na(V)1.6 channels lead to distinct contribu...

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Detalles Bibliográficos
Autores principales: Kotler, Oron, Khrapunsky, Yana, Shvartsman, Arik, Dai, Hui, Plant, Leigh D, Goldstein, Steven AN, Fleidervish, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014073/
https://www.ncbi.nlm.nih.gov/pubmed/36794908
http://dx.doi.org/10.7554/eLife.81463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014073/
https://www.ncbi.nlm.nih.gov/pubmed/36794908
http://dx.doi.org/10.7554/eLife.81463

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