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Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation()

BACKGROUND: Ginsenoside compound K (CK) stimulated activation of the PI3K-Akt signaling is one of the major mechanisms in promoting cell survival after stroke. However, the underlying mediators remain poorly understood. This study aimed to explore the docking protein of ginsenoside CK mediating the...

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Detalles Bibliográficos
Autores principales: Fu, Jing, Yu, Liang, Yu, Qian, Yu, Nengwei, Xu, Fei, Li, Suping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014182/
https://www.ncbi.nlm.nih.gov/pubmed/36926615
http://dx.doi.org/10.1016/j.jgr.2022.08.005