Notoginseng leaf triterpenes ameliorates mitochondrial oxidative injury via the NAMPT-SIRT1/2/3 signaling pathways in cerebral ischemic model rats

Background: Due to the interrupted blood supply in cerebral ischemic stroke (CIS), ischemic and hypoxia results in neuronal depolarization, insufficient NAD+, excessive levels of ROS, mitochondrial damages, and energy metabolism disorders, which triggers the ischemic cascades. Currently, improvement...

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Detalles Bibliográficos
Autores principales: Xie, Weijie, Zhu, Ting, Zhou, Ping, Xu, Huibo, Meng, Xiangbao, Ding, Tao, Nan, Fengwei, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014186/
https://www.ncbi.nlm.nih.gov/pubmed/36926612
http://dx.doi.org/10.1016/j.jgr.2020.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014186/
https://www.ncbi.nlm.nih.gov/pubmed/36926612
http://dx.doi.org/10.1016/j.jgr.2020.11.004

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