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Notoginseng leaf triterpenes ameliorates mitochondrial oxidative injury via the NAMPT-SIRT1/2/3 signaling pathways in cerebral ischemic model rats
Background: Due to the interrupted blood supply in cerebral ischemic stroke (CIS), ischemic and hypoxia results in neuronal depolarization, insufficient NAD+, excessive levels of ROS, mitochondrial damages, and energy metabolism disorders, which triggers the ischemic cascades. Currently, improvement...
Autores principales: | Xie, Weijie, Zhu, Ting, Zhou, Ping, Xu, Huibo, Meng, Xiangbao, Ding, Tao, Nan, Fengwei, Sun, Guibo, Sun, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014186/ https://www.ncbi.nlm.nih.gov/pubmed/36926612 http://dx.doi.org/10.1016/j.jgr.2020.11.004 |
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