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ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking in Ciona notochord

Lumen development is a crucial phase in tubulogenesis, although its molecular mechanisms are largely unknown. In this study, we discovered an ELMO domain-containing 3 (ELMOD3), which belongs to ADP-ribosylation factor GTPase-activating protein family, was necessary to form the notochord lumen in Cio...

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Detalles Bibliográficos
Autores principales: Liu, Amei, Ouyang, Xiuke, Wang, Zhuqing, Dong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014252/
https://www.ncbi.nlm.nih.gov/pubmed/36918025
http://dx.doi.org/10.1098/rsob.220367