Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes

DPP4 has been shown to induce diabetes-associated mitochondrial dysfunction and cognitive impairment through its non-canonical function. Here, we report that enhanced DPP4 expression in diabetes contributes to IP3R2-mediated mitochondria-associated ER membrane (MAM) formation, mitochondria calcium o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jiaxiu, Hui, Ya, Xu, Zhiqiang, Tan, Jie, Yin, Kai, Kuang, Liuyu, Tang, Yunyun, Wei, Junjie, Zhong, Qiongsui, Zheng, Tianpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014273/
https://www.ncbi.nlm.nih.gov/pubmed/36936785
http://dx.doi.org/10.1016/j.isci.2023.106271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014273/
https://www.ncbi.nlm.nih.gov/pubmed/36936785
http://dx.doi.org/10.1016/j.isci.2023.106271

Ejemplares similares