A FRET sensor for the real-time detection of long chain acyl-CoAs and synthetic ABHD5 ligands

Intracellular long-chain acyl-coenzyme As (LC-acyl-CoAs) are thought to be under tight spatial and temporal controls, yet the ability to image LC-acyl-CoAs in live cells is lacking. Here, we developed a fluorescence resonance energy transfer (FRET) sensor for LC-acyl-CoAs based on the allosterically...

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Detalles Bibliográficos
Autores principales: Mottillo, Emilio P., Mladenovic-Lucas, Ljiljana, Zhang, Huamei, Zhou, Li, Kelly, Christopher V., Ortiz, Pablo A., Granneman, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014278/
https://www.ncbi.nlm.nih.gov/pubmed/36936069
http://dx.doi.org/10.1016/j.crmeth.2023.100394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014278/
https://www.ncbi.nlm.nih.gov/pubmed/36936069
http://dx.doi.org/10.1016/j.crmeth.2023.100394

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