Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence

The flip-excision switch (FLEX) system with an adeno-associated viral (AAV) vector allows expression of transgenes in specific cell populations having Cre recombinase. A significant issue with this system is non-specific expression of transgenes in tissues after vector injection. We show here that C...

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Detalles Bibliográficos
Autores principales: Matsushita, Natsuki, Kato, Shigeki, Nishizawa, Kayo, Sugawara, Masateru, Takeuchi, Kosei, Miyasaka, Yoshiki, Mashimo, Tomoji, Kobayashi, Kazuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014282/
https://www.ncbi.nlm.nih.gov/pubmed/36936079
http://dx.doi.org/10.1016/j.crmeth.2022.100393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014282/
https://www.ncbi.nlm.nih.gov/pubmed/36936079
http://dx.doi.org/10.1016/j.crmeth.2022.100393

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