Cargando…
Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence
The flip-excision switch (FLEX) system with an adeno-associated viral (AAV) vector allows expression of transgenes in specific cell populations having Cre recombinase. A significant issue with this system is non-specific expression of transgenes in tissues after vector injection. We show here that C...
Autores principales: | Matsushita, Natsuki, Kato, Shigeki, Nishizawa, Kayo, Sugawara, Masateru, Takeuchi, Kosei, Miyasaka, Yoshiki, Mashimo, Tomoji, Kobayashi, Kazuto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014282/ https://www.ncbi.nlm.nih.gov/pubmed/36936079 http://dx.doi.org/10.1016/j.crmeth.2022.100393 |
Ejemplares similares
-
Protocol for highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence in rodents
por: Matsushita, Natsuki, et al.
Publicado: (2023) -
Combi-CRISPR: combination of NHEJ and HDR provides efficient and precise plasmid-based knock-ins in mice and rats
por: Yoshimi, Kazuto, et al.
Publicado: (2020) -
A high-quality severe combined immunodeficiency (SCID) rat bioresource
por: Miyasaka, Yoshiki, et al.
Publicado: (2022) -
Genetic deletion of the 67‐kDa isoform of glutamate decarboxylase alters conditioned fear behavior in rats
por: Fujihara, Kazuyuki, et al.
Publicado: (2020) -
Thalamostriatal System Controls the Acquisition, Performance, and Flexibility of Learning Behavior
por: Kato, Shigeki, et al.
Publicado: (2021)