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Mass spectrometry quantitation of immunosuppressive drugs in clinical specimens using online solid-phase extraction and accurate-mass full scan-single ion monitoring

INTRODUCTION: Therapeutic drug monitoring (TDM) of immunosuppressants is essential for optimal care of transplant patients. Immunoassays and liquid chromatography-mass spectrometry (LC-MS) are the most commonly used methods for TDM. However, immunoassays can suffer from interference from heterophile...

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Detalles Bibliográficos
Autores principales: Yeung, Priscilla S.-W., Miller, Paige, Lai-Nyugen, Tran Bao, Cheng, Phil, Ibrahim, Amira, Shi, Run-Zhang, Bowen, Raffick A.R., Luo, Ruben Yiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014293/
https://www.ncbi.nlm.nih.gov/pubmed/36937810
http://dx.doi.org/10.1016/j.jmsacl.2023.03.002