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A hybrid deep forest-based method for predicting synergistic drug combinations

Combination therapy is a promising approach in treating multiple complex diseases. However, the large search space of available drug combinations exacerbates challenge for experimental screening. To predict synergistic drug combinations in different cancer cell lines, we propose an improved deep for...

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Detalles Bibliográficos
Autores principales: Wu, Lianlian, Gao, Jie, Zhang, Yixin, Sui, Binsheng, Wen, Yuqi, Wu, Qingqiang, Liu, Kunhong, He, Song, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014304/
https://www.ncbi.nlm.nih.gov/pubmed/36936075
http://dx.doi.org/10.1016/j.crmeth.2023.100411