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DNA-methylation and genomic copy number in primary tumors and corresponding lymph node metastases in prostate cancer from patients with low and high Gleason score

PURPOSE: In prostate cancer, the indication to irradiate the pelvic lymphatic pathways in clinical node-negative patients is solely based on clinical nomograms. To define biological risk patterns of lymphatic spread, we studied DNA-methylation and genomic copy number in primary tumors and correspond...

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Detalles Bibliográficos
Autores principales: Unger, Kristian, Hess, Julia, Link, Vera, Buchner, Alexander, Eze, Chukwuka, Li, Minglun, Stief, Christian, Kirchner, Thomas, Klauschen, Frederick, Zitzelsberger, Horst, Niyazi, Maximilian, Ganswindt, Ute, Schmidt-Hegemann, Nina-Sophie, Belka, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014335/
https://www.ncbi.nlm.nih.gov/pubmed/36935856
http://dx.doi.org/10.1016/j.ctro.2023.100586