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DNA-methylation and genomic copy number in primary tumors and corresponding lymph node metastases in prostate cancer from patients with low and high Gleason score
PURPOSE: In prostate cancer, the indication to irradiate the pelvic lymphatic pathways in clinical node-negative patients is solely based on clinical nomograms. To define biological risk patterns of lymphatic spread, we studied DNA-methylation and genomic copy number in primary tumors and correspond...
Autores principales: | Unger, Kristian, Hess, Julia, Link, Vera, Buchner, Alexander, Eze, Chukwuka, Li, Minglun, Stief, Christian, Kirchner, Thomas, Klauschen, Frederick, Zitzelsberger, Horst, Niyazi, Maximilian, Ganswindt, Ute, Schmidt-Hegemann, Nina-Sophie, Belka, Claus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014335/ https://www.ncbi.nlm.nih.gov/pubmed/36935856 http://dx.doi.org/10.1016/j.ctro.2023.100586 |
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