High-efficiency pharmacogenetic ablation of oligodendrocyte progenitor cells in the adult mouse CNS

Approaches to investigate adult oligodendrocyte progenitor cells (OPCs) by targeted cell ablation in the rodent CNS have limitations in the extent and duration of OPC depletion. We have developed a pharmacogenetic approach for conditional OPC ablation, eliminating >98% of OPCs throughout the brai...

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Detalles Bibliográficos
Autores principales: Xing, Yao Lulu, Poh, Jasmine, Chuang, Bernard H.A., Moradi, Kaveh, Mitew, Stanislaw, Richardson, William D., Kilpatrick, Trevor J., Osanai, Yasuyuki, Merson, Tobias D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014347/
https://www.ncbi.nlm.nih.gov/pubmed/36936074
http://dx.doi.org/10.1016/j.crmeth.2023.100414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014347/
https://www.ncbi.nlm.nih.gov/pubmed/36936074
http://dx.doi.org/10.1016/j.crmeth.2023.100414

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