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Intrahepatic infiltration of activated CD8(+) T cells and mononuclear phagocyte is associated with idiosyncratic drug-induced liver injury

BACKGROUND: Idiosyncratic drug-induced liver injury (DILI) is caused by the interplay among drugs, their metabolites, and the host immune response. The characterization of infiltrated immune cells in the liver may improve the understanding of the pathogenesis of idiosyncratic DILI. This study invest...

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Detalles Bibliográficos
Autores principales: Yang, Hyun, Han, Ji Won, Lee, Jae Jun, Lee, Ahlim, Cho, Sung Woo, Rho, Pu Reun, Kang, Min-Woo, Jang, Jeong Won, Jung, Eun Sun, Choi, Jong Young, Sung, Pil Soo, Bae, Si Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014460/
https://www.ncbi.nlm.nih.gov/pubmed/36936915
http://dx.doi.org/10.3389/fimmu.2023.1138112