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Intrahepatic infiltration of activated CD8(+) T cells and mononuclear phagocyte is associated with idiosyncratic drug-induced liver injury
BACKGROUND: Idiosyncratic drug-induced liver injury (DILI) is caused by the interplay among drugs, their metabolites, and the host immune response. The characterization of infiltrated immune cells in the liver may improve the understanding of the pathogenesis of idiosyncratic DILI. This study invest...
Autores principales: | Yang, Hyun, Han, Ji Won, Lee, Jae Jun, Lee, Ahlim, Cho, Sung Woo, Rho, Pu Reun, Kang, Min-Woo, Jang, Jeong Won, Jung, Eun Sun, Choi, Jong Young, Sung, Pil Soo, Bae, Si Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014460/ https://www.ncbi.nlm.nih.gov/pubmed/36936915 http://dx.doi.org/10.3389/fimmu.2023.1138112 |
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