Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing

The control of severe or chronic pain has relied heavily on opioids and opioid abuse and addiction have recently become a major global health crisis. Therefore, it is imperative to develop new pain therapeutics which have comparable efficacy for pain suppression but lack of the harmful effects of op...

Descripción completa

Detalles Bibliográficos
Autores principales: Nimbalkar, Siddharth, Guo, Xiufang, Colón, Alisha, Jackson, Max, Akanda, Nesar, Patel, Aakash, Grillo, Marcella, Hickman, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014464/
https://www.ncbi.nlm.nih.gov/pubmed/36936691
http://dx.doi.org/10.3389/fcell.2023.1011145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014464/
https://www.ncbi.nlm.nih.gov/pubmed/36936691
http://dx.doi.org/10.3389/fcell.2023.1011145

Ejemplares similares