Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion

Downregulation of cell–cell adhesion and increased motility are prerequisites for the metastasis of cancer cells. We have recently shown that downregulation of the tight junction adapter protein Pals1 in colorectal cancer cells results in an increase of cell migration, invasion, and metastasis due t...

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Detalles Bibliográficos
Autores principales: Harms, Julia, Lüttgenau, Simona Mareike, Emming, Christin, Guske, Justine, Weber, Katrin, Wagner, Thomas, Schowe, Larissa, Nedvetsky, Pavel, Krahn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014575/
https://www.ncbi.nlm.nih.gov/pubmed/36494580
http://dx.doi.org/10.1038/s41417-022-00570-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014575/
https://www.ncbi.nlm.nih.gov/pubmed/36494580
http://dx.doi.org/10.1038/s41417-022-00570-2

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