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Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes

Accurate chromosome segregation during meiosis is crucial for reproduction. Human and porcine oocytes transiently cluster their chromosomes before the onset of spindle assembly and subsequent chromosome segregation. The mechanism and function of chromosome clustering are unknown. Here we show that c...

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Detalles Bibliográficos
Autores principales: Harasimov, Katarina, Uraji, Julia, Mönnich, Eike Urs, Holubcová, Zuzana, Elder, Kay, Blayney, Martyn, Schuh, Melina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014578/
https://www.ncbi.nlm.nih.gov/pubmed/36732633
http://dx.doi.org/10.1038/s41556-022-01082-9